Innovative research can often be the decisive factor in the fight against blood cancer. This fight can only be won if new scientific approaches are found to combat the disease.
“Apart from being the World’s leading stem cell donor, DKMS is also avidly involved in medical science. We have an exceptionally qualified research team working in our very own high-performance laboratory called DKMS Life Science Lab. With our quality programs and various other research programs, we are driven by our mission which is to provide scores of people, who are suffering from blood cancer or some form of blood disorders, a second chance at life. This multifaceted approach helps us to fight blood cancer from every angle.
We are committed to make blood stem cell transplants a lasting success. We are therefore investing our time and money in conducting research that will help us solve numerous unanswered questions in the science of blood cancer.”
John Hansen Research Grant
An important element of our endeavour consists of promoting young researchers. Since 2015, our annual John Hansen Research Grant (known until 2019 as the Mechtild Harf Research Grants) is awarded every year to as many as four talented young scientific researchers.
In 2001, the DKMS Stiftung Leben Spenden (Foundation for Giving Life) began awarding the DKMS Mechtild Harf Science Award annually at the congress of the European Group for Blood and Marrow Transplantation (EBMT). The award recognizes outstanding research achievements in the field of blood cancer treatment and is regarded by scientists and physicians as a prestigious commendation.
DKMS’s Clinical Trials Unit (CTU) actively works to drive scientific progress in the fight against blood cancer and to launch innovative, lifesaving research projects as well as support existing ones. Our research focuses on allogeneic blood stem cell transplantation, in which the cells come from an unrelated donor. This means much of our work is in an area that is of little interest to the pharmaceutical industry and therefore under-resourced.
The more efficiently we work, the faster patients can be treated. Thus, we are constantly striving to develop and improve the quality and quantity of the DKMS database and its donor date. We have significantly improved it already, by developing our own search algorithm.
The DKMS Life Science Lab, the global leader in HLA typing, analyzes cheek swab or blood samples from potential stem cell donors around the world. Accredited pursuant to international guidelines (ASHI and EFI), it is the world's most innovative and most efficient tissue (HLA) typing laboratory. Our experts at the DKMS Life Science Lab carry out typing according to the latest scientific standards continuously expanding typing profiles. The state-of-the-art workflow is deploying Next Generation Sequencing (NGS) to enable the analysis of well over one million samples per year.
The DKMS Stem Cell Bank is another important developmental step when it comes to helping patients worldwide even faster. Often the amount of blood stem cells taken from a donor exceeds the needs of the patient who requires them for the transplantation. With the donors' consent, these surplus cells are now frozen, or cryopreserved as scientists would refer to it, rather than disposed of. They are then available to blood cancer patients worldwide for a possible further life-saving transplantation. That way our donors can potentially save two lives with one donation. We will fully inform our donors who are eligible for a stored donation in the DKMS Stem Cell Bank in advance and ask for an additional declaration of consent.
DKMS was founded in 1991 as donor center and has in addition to this established its donor registry in 2015. As an official registry, we have been listing DKMS-BMST donors from India since 2015 and DKMS donors from Chile since 2018. Listing means that we are storing the information of our donors’ tissue characteristics in pseudonymized form and make them available for worldwide searches for the best possible match between donor and patient. Since 2020 the DKMS Registry operates as an independent subsidiary of DKMS.